Observational, open studies with well-chosen patients and an adequate design tailored to answer precise predefined questions (including go/no go criteria) are most valuable for experienced clinicians in determining the clinical benefit of the drug, and for the pharmaceutical company in assessing the commercial merit of proceeding with further clinical testing.
It should be possible for the larger (and incredibly heated) debate over the merits of Obamacare to proceed even while specific flaws in the legislation are addressed to avoid unintended harms to thousands of Congressional employees or millions of vulnerable families.
They also argue that punitive measures don't work, and that the settlement is nothing more than punitive because it doesn't relate to the merits of any given foreclosure proceeding.
This randomised phase II study aimed at assessing the relative merits of both regimens before proceeding to a full phase III study.
Possible solutions might include requiring an expert judgment on the merits of a case before it proceeds to court, guidelines to help judges and juries determine reasonable compensation, special health courts with highly trained judges to sift through the evidence and added protection for doctors who follow best-practice guidelines.
Liberals would find much to dispute, but a dispute could proceed on the merits of Romney's national security perspective weighed against Obama's.
But precisely because it is so important, that's a debate that should proceed on the merits of the arguments and not as a proxy for an entirely different discussion.
Policy makers generally lead these processes, but are subject to decisions by fund holders and political leaders, who must be convinced of the relevant merits of action before any action can proceed; a theme that is consistent with the global health literature [ 12, 22].
Proceeding to the merits of the petitions, the court then ruled against the two men, Mohammad Munaf and Shawqi Ahmad Omar, who are facing criminal charges under Iraqi law.
When we consider the merits of the present system and how to proceed, we are actually debating what to do about low investment returns and high healthcare costs.
