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As reported previously, 5 assessment of initial screening hits against human GR and T. brucei cells together with in silico analysis of chemical properties revealed three new classes of TryR inhibitors that merited further development.
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Ligand 2 was concluded to merit further development for KOR exploration.
Visibility aids have the potential to improve detection and recognition and would merit further development to gain public acceptance.
High PHA content, productivity, zero-cost carbon source, low-cost of isolation of a high-purity product and potential for integration into ethanol manufacturing unit would merit further development of this process to higher scales.
High PHA content, productivity, zero-cost carbon source, low-cost isolation of a high-purity product and potential integration into ethanol manufacturing unit with concomitant wastewater treatment should merit further development of this process to higher scales.
With a concise efficient synthesis and potent cytotoxic profiles, especially significant activity towards KBvin, these compounds merit further development as a new generation of CPT-derived PEG-conjugated drug candidates.
The present state of application of the materials is still largely in the academic domain but increasingly, new structures with the necessary proton conducting ability and stability to merit further development as membranes are being reported.
Point-Of-Care diagnostic technologies can also have a part in reducing the number of consultations before referral, and such tests merit further development and evaluation.
This compound class merits further development as anticancer clinical trial candidates.
Compounds 12a b merit further development as potent clinical trial candidates against AIDS.
Overall, the naphthyl-based mannoside ligand (37A) showed the best activity and therefore merits further development.
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