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And matters could become far more serious than a mere loss of voters' support.
You can claim financial hardship -- mere loss of income doesn't fly -- if you bring in tax returns and documentation of employment status.
But if they do, it will probably need to be forced by Mr. Romney's campaign, or by developments in the news cycle, not the mere loss of post-convention momentum.
It is usually accepted that the mere loss of decision-making capacity is insufficient (Dworkin 1993, 222-29).
As in other roguelikes, the sting of defeat has as much to do with the abandonment of a particular tale, a particular world, as it is the mere loss of progress.
SecTRAPs are prooxidant killers of cells, triggering mechanisms beyond those of a mere loss of thioredoxin reductase activity.
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The biological consequences of p53 mutations range from the mere loss-of-function to gain-of-function.
Therefore, the altered pattern of MBNL1 expression may further contribute to the multisystemic manifestation of DM not only through the mere loss-of-function due to the titration of the RNA-binding proteins by the CUG expansions.
Although the idea that missense mutations can confer oncogenic properties to p53, in contrast to a mere loss-of-function, has been around for many years(22 24), only specific mouse models have proved that mutant p53 gain-of-function (GOF defined as the ability of p53 missense mutants to actively contribute to tumor progression and aggressiveness indeed affects tumorigenesis in vivo.
Although the phenotype of the (CTG 240.4 line cannot be explained by a mere loss or gain of function of CG9650, both (CUG 240.4 RNA induction (as shown in this work), and CG9650 over-expression affect the nervous system and the eye [20], [21].
It can be a mere loss at peripheral that affects only the value of islet size nβ.
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