Sentence examples for mere binding of from inspiring English sources

In fact, the mere binding of uPA on the cell surface also brings about two events that broaden the spectrum of its biological functions: (1) a conformational change of the receptor, which, in turn, affects its interaction with other proteins; (2) a signal transduction which modulates the expression of apoptosis-related genes.

Whether the neurons are distressed by mere binding of Aβ proteins to the neuronal membrane or by internalization of the Aβ proteins that trigger cellular events that eventually lead to synaptic loss and neurodegeneration needs further resolution.

Our data further suggest that a mere binding of a translocating species to FG domains is insufficient for facilitated passage.

However, the mere binding of an NR to its ligand does not ensure its adoption until the physiological relevance of the molecule is validated.

Previous reports provide mixed evidence that Baculovirus expressed membrane proteins indeed are active, and some reports claim functionality based on the mere binding of an inhibitor to the protein, and without demonstrating actual functionality (11- 16).

p53 is a sequence-specific transcription factor that can bind to several target promoters but in few cases it has been suggested that mere binding of a transcription factor to a specific genomic sequence does not necessarily imply direct transcriptional regulation.

Fluorescence microscopic observations revealed actual uptake of AML preparations and not mere binding to DC cell surface (Fig.  1b).

In addition to mere binding to host cells, CEACAM engagement triggers endocytosis of the bacteria into epithelial cells and transcytosis of microorganisms through intact epithelial layers [ 53, 58, 59].

In fact, one would expect that a mere binding causes retention of NTRs and therefore slows down their passage.

Given the physiological level of fluidity in our supported membrane arrays, it is possible to study ligand/receptor interactions in a manner beyond capturing mere binding data.

It is conceivable that in some cases the CBM33s have a mere binding function.