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The geometric mean cord to maternal blood mercury ratio was 1.79 to 1. Increasing maternal fish consumption and maternal age were found to be associated with increased cord blood mercury concentrations.
We also varied the cord:maternal blood mercury ratio from 1 to 1.7 in calculating IQ impact from the linear model as part of our sensitivity analysis.
The cord:maternal mercury ratio was significantly higher for fish eaters than for non-fish eaters, whereas it was not higher for China-born than for non-China-born Asian women.
Using our base-case assumptions (impact for women with total mercury > 4.84 μg/L, cord:maternal mercury ratio = 1.7, IQ impact = 1.5 points per doubling), we calculated costs for the 405,881 children who suffer IQ decrements resulting from fetal methyl mercury exposure.
I am very interested in the details of this analysis and particularly in understanding why the uncertainty factor applied by the NRC to account in part for toxicokinetic variability does not compensate for uncertainty related to the cord blood:maternal blood mercury ratio.
Virtanen et al. (2005) observed increased CV events in a mercury-exposed population with an average hair mercury level of 1.9 μg/g (0 15.7 μg/g), which is estimated to indicate a blood mercury level of 9.5 μg/L (0.05 μM) based on a 200 1 hair-to-blood mercury ratio (Budtz-Jorgensen et al. 2004).
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By using the experimental design (DoE) technique, we optimized an analytical method for the determination of mercury isotope ratios by means of cold-vapor multicollector ICP-MS (CV-MC-ICP-MS) to provide absolute Hg isotopic ratio measurements with a suitable internal precision.
There were no statistically significant differences between groups in urine mercury:creatinine ratios (Table 2).
Mercury isotope ratios have recently been used to provide insight into the sources and exposure pathways of MMHg to diverse marine food webs.
(1) Herein we report that as the diameter of AgNPs is reduced below 32 nm, mercury II) is reduced from water onto AgNPs with the mercury-to-silver ratio reaching 1.125 1 for 11 nm AgNPs.
We measured mercury (Hg) isotope ratios in sediments and various estuarine organisms (green crab, blue mussel, killifish, eider) to investigate methylmercury (MMHg) sources and exposure pathways in five Northeast coast (U.S).
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