As previously mentioned, well-differentiated HCCs were confirmed microscopically in all mice after 15 weeks (Time point II) of CCl4 treatment; however, most notably, no evidence of cirrhosis (i.e. the presence of regenerative nodules) was identified in these livers, even in those with HCC.
Therefore, tumours were classified into histological prognostic groups based on type and grade where mentioned: good prognosis (ductal grade I, well differentiated and special types e.g. tubular), moderate prognosis (ductal grade II, no comment, or lobular) and poor prognosis (poorly differentiated or ductal grade III).
Histologically, 11% of the samples were well differentiated, 33% moderately well differentiated and 56% poorly differentiated.
Histological features (Grade of differentiation); well: well differentiated; mod: moderately well differentiated; poor: poorly differentiated.
Tumour differentiation (grade) was classified as well differentiated (grade 1), moderately differentiated (grade 2) and poorly differentiated (grade 3).
Histology showed polypoid type I gastric well differentiated NETs, while the histopathological examination of the remaining stomach's excision specimen documented the co-existence of a GIST (risk category not mentioned) [ 7].
The task here is differential diagnosis of three histological types: poorly differentiated, 14; moderately differentiated, 97; well differentiated, 30.
The vertebral column was well differentiated.
Supplementary Figure 1 Subcutaneous and orthotopically grafted xenograft models are well differentiated.
The leaf sheath is not well differentiated except in Freycinetia, and petioles are absent.
The biopsy of the tumor indicated well differentiated adenocarcinoma.
