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The mentioned analysis was fortified by ANOVA, images of FESEM, and DSC results.

All the above mentioned analysis was performed using molecular imaging and kinetic analysis toolbox (MIAKAT™, version 4.0.2, http://www.miakat.org/MIAKAT2/index.html).html

The mentioned analysis was conducted for each of individual MIR family and separately for group of all conserved and novel miRNAs.

Though the results of our previously mentioned analysis was intriguing, further characterizing the functional features of the biliary tract microbiome via a culture approach proved quite difficult.

Only individuals with one sibling were, however, included in these subanalyses and because of register-coverage and number of cases, the last mentioned analysis was only performed on breast cancer.

Besides, the above-mentioned analysis is carried out based on propensity score matching techniques.

Encouraged by this, whole transcriptome analysis for miRNA targets in rice transcriptome sequences was carried out, excluding those sequences on which the above mentioned analysis had been performed already in order to avoid redundancy, looking for new targets and save time.

In the above mentioned analysis plan it is assumed that the children will play the game individually and that therefore the data will not be clustered.

Unless otherwise mentioned, statistical analysis was done using an unpaired one-tailed Student's t-test.

Unless otherwise mentioned, the analysis was performed using pair-wise moderate t-test with cut-off p < 0.05.

If not mentioned, statistical analysis was conducted using IBM SPSS version 20.0 software (IBM, Armonk, NY, USA).

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