"The key warning signs that Francis mentioned - accumulation of patient stories detailing adverse incidents, bad practice, unusually high mortality statistics, signals from staff and whistleblowers, poor governance dysfunctional hospital wards and also weak regulation.
As mentioned above, accumulation of estrogen receptor protein (induced by MG132 or Akt) can lead, depending on the context, to a decrease of transactivation, but on the contrary, the threshold under which the ER protein level reduction could alter its recruitment to promoters is not clearly defined and might be dependent upon the cellular context.
But just because we have tucked one generation of wine enjoyment under our bibs doesn't mean that we always feel at home with the stuff, not to mention the accumulation of strange customs.
It is important to mention that accumulation of misfolded proteins in the ER lumen may elicit the unfolded protein response (UPR) signal transduction pathway (Ref. 126).
However, since the reconstruction artefacts previously mentioned cause an accumulation of signal in the object at its borders, they may also have an impact on the behaviour of a segmentation algorithm based on a surface being attracted to that edge.
It eventually found expression in a particularly vehement form in the writing of Martin Luther which Marx cites at the same point in the text of Capital as that at which he intones his sarcastic paean to accumulation, mentioned above.
As mentioned before, the accumulation of multiple aa substitutions in F or HN proteins may also result from the immune pressure that can contribute to increase the phylogenetic distance between the MG group and its progenitor genotype.
As mentioned above, nuclear accumulation of β-catenin represents a key event in CRC progression.
However, as mentioned earlier, the accumulation of cytotoxic NK cells was not affected by αIL-22 (data not shown), and neutrophil depletion did not impair NK cell accumulation, cytotoxicity or IFN-γ expression.
As it was mentioned before, phytohormones accumulation change after virus infection [ 45, 46] and putative phytohormone-responsive elements were detected in the P-miR164a sequence by in silico analysis (Table 1).
