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The negative slow wave correlated significantly with the 1-year Mental Developmental Index.
Case subjects had a mental developmental index <70, and controls had a mental developmental index ≥85, according to the Bayley Scales of Infant Development II at 18 months' corrected age.
Infants with intracranial hemorrhage (23%) had significantly lower mental developmental index and psychomotor developmental index scores than infants with no intracranial hemorrhage, independent of antenatal phenobarbital exposure.
In the total cohort of 436 infants, the presence of intracranial hemorrhage or periventricular leukomalacia was associated with lower mental developmental index and psychomotor developmental index scores; the presence of increasing birth weight, maternal education, and a complete course of antenatal steroids was associated with a higher mental developmental index score.
Study Design: Infants were evaluated at 18 to 22 months corrected age with a standard neurologic examination and the Bayley scales of infant development measuring the mental developmental index and the psychomotor developmental index.
The mean Bayley Scales of Infant Development scores were as follows: Mental Developmental Index score, 95.6 (14.5); Psychomotor Developmental Index score, 97.9 (14.8); and Behavioural Rating Scale score, 110.6 (110.6.
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Results The Bayley mental developmental indexes were similar in both groups.
Mental and psychomotor developmental indices (MDI, PDI) were determined with the Bayley Scales of Infant Development I: ≥−1 S.D.: normal, −2 to −1 S.D.: moderate delay and <−2 S.D.: severe delay.
Objectives: Our goal was to explore the association between prenatal di 2-ethylhexyl) phthalate andi 2-ethylhexyllate exphthalated the Mentandandibutylomotor Develophthalatendicexposureand PDI, respectheely) of the Bayley Scales of Infant DevelopMentalt 6 months, andPsychomotor Mothers anDevelopmentalEnvIndicestal Health Study.
In this study, we hypothesized that prenatal exposure to di 2-ethylhexyl) phthalate (di 2-ethylhexylyl phthalate (DEHP would be inversely andociatedibutylMental and phthalateor DBPelopmental Indices (MDI and PDI, respectively), as measured by the Korean Bayley Scales of Infant Development, 2nd edition (BSID-II) at 6 months (Bayley 1993; Park and Cho 2006).
Similarly, a recent Duisburg birth cohort study in Germany (median PCDD/PCDFs) [WHO 2005 TEQ = 11 pg/g lipid in breast milk (Van den Berg et al. 2006)] did not find an inverse association with mental and psychomotor developmental indexes at 12 and 24 months of age (Van den Berg et al. 2006 Wilhelmm et al. 2008).
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