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[24], [26] The independent variables of interest were: circumcision group (men randomized to receive circumcision versus those randomized to remain uncircumcised); time (indicator variables for 6 month and 12 month follow-up); and the interaction between circumcision group and time.
Moreover, many of the men randomized to the control group continued to have PSA tests irrespective of randomized assignment: 40% of men in the control group received a PSA test in the first year after randomization.
Although most studies found no association between alcohol intake and prostate cancer (PCa) risk, an analysis of the Prostate Cancer Prevention Trial found that high alcohol intake significantly increased PCa risk among men randomized to the 5α-reductase inhibitor (5-ARI) finasteride.
There were 84 men randomized to receive clodronate or placebo (McCloskey et al 1999).
Patient reported urinary incontinence and erectile dysfunction, but not bowel dysfunction, were more common at two years in men randomized to surgery.
The first of these trials (MRC PR05), published in 2003, assessed 311 men randomized to clodronate 2,080 mg daily (as four 520 mg tablets) or matching placebo.
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Two deaths occurred during the double-blind period: a 29-year-old Caucasian woman randomized to placebo died of acute respiratory failure after being diagnosed with pneumonia; and a 27-year-old Caucasian man randomized to ESL 800 mg was found dead in bed with a bitten tongue (during the titration phase, while receiving 400 mg ESL).
More Child-Pugh class C patients were randomized to GPB than to placebo (21 versus 8, respectively), and fewer men were randomized to GPB than to placebo (45 versus 59; Table 1).
In the gay-identified group, 142 men were randomized to the video-based intervention and 130 to the text-based intervention (Figure 1).
In the gay-identified group, 142 men were randomized to the video-based intervention and 130 to the text-based intervention.
The men were randomized to 4 mg IV annual zoledronic acid or placebo.
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