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6 days later, the paired-associate memory was reactivated by exposing the subjects to the reminder, and then they received a mild stressor, cold pressor stress (CPS).
The appropriate neural activity for that "forgotten" item spiked, showing the memory was reactivated into immediate consciousness from its latent state.
However, GSK+/− mice failed to achieve reconsolidation when the memory was reactivated once before testing.
Third, in previous similar studies, the fear memory was reactivated by the CS (tone) that was intermingled with the shock context because the freezing behaviors were measured in the same shock chamber [14], [16].
In contextual fear conditioning (CFC), context memory was normally consolidated in GSK+/− mice, but once the original memory was reactivated, they showed reduced freezing, suggesting that GSK+/− mice had impaired memory reconsolidation.
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Moreover, in line with the reconsolidation hypothesis, which proposes that when a memory is reactivated, the trace may return to a labile state after which time it is reconsolidated or restabilized, the idea was that the requirement for reconsolidation would further strengthen learning (Feld & Diekelmann, 2015).
"Recalling a memory is reactivating a specific set of synapses".
Research with both rodents and people has suggested that new memories are reactivated during sleep (Science, 9 March 2007, p. 1360).
"We are quite certain that memories are reactivated in the brain during sleep, but we don't know the neural processes that underpin this phenomenon," Scott Cairney, a professor of psychology at the University of York, said in a statement.
At the same time, they monitored the electrical activity in the subjects' brain with an electroencephalogram (EEG) and found that sleep spindles were triggered when memories were reactivated by the words.
Autobiographical memories were reactivated by means of the autobiographical memory cueing test [16].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com