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On the plus side, the generalization from these results to actual eyewitness memory is more straightforward than if a more traditional list-based laboratory memory task had been used.
This applied even when the long-term memory task had no auditory component.
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Models of PFC neurons' persistent firing during a working memory task have demonstrated that this dopamine-mediated increase in gain acts to stabilize persistent activity and protect it from interference [35].
In line with this assumption, processing of gist and detail information in an emotional memory task has been related to hormonal status of participants (Nielsen et al., 2011).
The nonconfigural version of our working memory task has the closest correspondence to a working memory study in nonhuman primates demonstrating theta-coupled replay in visual area V4 [ 9].
A reduction of the amplitude of the P3b component during encoding and retrieval on a visual working memory task has been reported in patients with early-onset (adolescent) schizophrenia [ 53].
The early impairment of amygdala structures, whose central role in the recognition and memorization of emotions has been demonstrated, has been associated with deficits in terms of social cognition in AD. 37 Furthermore, positron emission tomography studies in AD patients during face memory task have pointed toward dysfunction of the amygdala.
In a recent twin study (Blokland et al., 2011), functional MRI activation patterns during the n-back working memory task have been shown to be significantly heritable and regions of interest identified here, i.e. the precentral gyrus and supplementary motor area, have been among the regions with the highest heritability estimates.
While behavioral studies using several different memory tasks have provided converging evidence for an influence of 5-HTR2a human2Tyr on humemorymory performance, the underlying neural correlates have thus far been unclear.
According to the authors, findings supported the neural efficiency hypothesis and suggested that the connections between brain areas of well-educated subjects engaged in working memory tasks have less small-world characteristics than those of less-educated volunteers.
14 Morris water maze and episodic-like memory tasks have been previously detailed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com