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Homeostatic proliferation of infected transitional memory T cells (6) has been proposed as a source that could maintain the pool, but this does not explain persistence in the dominant central memory reservoir.
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As The Times wrote in 1898, even the memory of the reservoir was destined "to be cast aside now that the limitless thirst of the population takes in the whole Croton Valley water supply".
Moreover, in two models of systemic lupus erythematosus, PI3Kγ was shown to control the CD4+ memory T cell reservoir mostly in the context of a second genetic alteration (MRL- lpr or p65PI3KTg), while single-targeted PI3Kγ-inhibition revealed only modest phenotypes [ 27, 29].
Reservoirs based on uniform spreading of connection matrix eigenvalues on the unit disk in discrete time give much better memory properties than reservoirs with random connection matrices, where reservoirs based on orthogonal connection matrices in discrete time are very robust against noise and their memory properties can be tuned.
"It's a reservoir of memory, tradition, and heritage".
Hoping to arouse interest in the program among students whose collective memory dates back to "Reservoir Dogs," he was co-host for a recent series of double bills with present-day film school idols: on the final night, David O. Russell ("Three Kings") helped him introduce "Sunset Boulevard" and "The Lost Weekend".
They analyzed the blood of patients with blips every two to three days over three to four months, and their hypothesis proved correct: the virus had not become resistant to the drugs, but had been dormant in its reservoir within memory T cells.
One of the important success criterion for any vaccine, is the formation of a reservoir of memory cells of both adequate size and quality to maintain efficient immune surveillance for prolonged periods.
In this model, too little antigen leads to suboptimal responses, whereas an over-abundance or prolonged expression of antigen leads to a suboptimal reservoir of memory T cells [22], [23], [24], [25].
The journey would be potentially endless, linking prisons, football stadiums, waste-disposal plants, cemeteries and reservoirs of memory.
The place was in his bones: "It is an article of faith with me", he writes, "that a place consists of everything that has happened there; it is a reservoir of memories".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com