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It is generally accepted that working memory processes support higher cognitive functions including reasoning.
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Therefore, any intrusion of stimulus-independent thoughts during the monotonous baseline conditions of repetitively producing single syllables or graphemes was insufficient to reduce activity associated with the linguistic and memory processes that support narrative production.
This finding may suggest a division of labor within the MTL with regard to memory processes and supports the value of both verbal and non-verbal memory measures in the assessment of those at risk for AD.
Verbal and visual memory processes most likely support verbal and spatial operations.
The current finding of profound deficits in novel object recognition following DA depletion in the core suggests that interactions between the perirhinal cortex and NAc contribute to consolidation of memory processes necessary to support novel object recognition.
These data provide further insight into cellular and molecular mechanisms by which FC may support memory processes in Alzheimer's disease.
2, 5, 76 In summary, our findings provide support for the hypothesis that Aβ is associated with local neurodegeneration in key nodes of a distributed network supporting memory processes, and that this process begins prior to clinically-evident cognitive impairment, but continues into the stage of clinical dementia.
Indeed, we have found that hippocampal activity mostly supports spatial memory processes, whereas activity in parahippocampal, frontal, posterior parietal and lateral temporal cortices supports the contextual memory component [13].
Recent studies have shown that the synaptic dynamics and local connectivity of the prefrontal cortex are specialized to provide sustained neuronal firing, as might be appropriate for supporting working memory processes (Goldman-Rakic 1995; Wang 2001; Gonzalez-Burgos et al. 2004).
A recent individual differences work found that people differ in their reliance on executive control processes, secondary memory processes, or simply spontaneous processes to support PM function [ 34].
This task also engaged frontotemporal auditory working memory processes (pitch and verbal) presumably to support the retention of tones "in mind" while associating their verbal labels.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com