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Mean performance was 76.9% at Lag 1, 74.2% at Lag 3, and 89.6% at Lag 8, reflecting an attentional blink with a degree of Lag 1 sparing, which was similar to Experiment 1. Performance with low memory load averaged 83.2%, while high memory load resulted in 77.4%.
In addition, high working memory load resulted in increased congruency-related functional connectivity between anterior cingulate cortex and V1.
Hinson, Jameson, & Whitney [ 35] reported that increasing working memory load resulted in poorer performance on the card task.
However, at 8 months of age, the more stringent memory load resulted in discrimination of performance between the R26CT and R26CT-CRE mice.
Increased working memory load resulted in enhanced distractor effects in primary visual cortex, the opposite effect to that previously seen for perceptual load (e.g., Schwartz et al. 2005), as we predicted.
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We have shown that reduced cognitive control under high working memory load results in extensive modulation of the distractor competition effects not only on behavior and on conflict resolution areas in frontoparietal cortex but also on the sensory correlates found in primary visual cortex areas V1 and V2.
It is important to note that this study was not designed to experimentally manipulate working memory load and, thus, our results make no claims as to the involvement of the hippocampus in working memory per se.
The similarities between the patterns of priming performance over the three memory load conditions are therefore speculated to result from a continuation in the strategic reduction in interhemispheric inhibition to continue to facilitate compensatory bilateral recruitment in older adults in each of the memory load conditions.
The interaction replicated the previously found result that memory load affects the attentional blink specifically [19].
This is consistent with studies of healthy individuals which have shown that increased working memory load can interact with the ability to sustain attention, resulting in premature vigilance decrements (Parasuraman, 1979; Caggiano and Parasuraman, 2004).
The opposite effects of different types of memory load rule out alternative accounts for these results in terms of a general increase in task difficulty.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com