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Thereby, in addition to a finer tuning, the altered transcript levels from the memory genes suggest an altered crosstalk between these pathways in S3 compared to S1. Non-memory ( and ) and unidirectional memory ( and ) dehydration stress responding genes respond every time the plant experiences dehydration stress.
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However, the different memory patterns displayed by the homologous genes suggest species-specific diversification of the responses to repeated stress occurring at the transcriptional level during their evolution.
It is logical to consider the biological relevance of and memory genes in this context, as suggested by the large numbers of metabolic functions encoded by revised response memory genes (Additional file 6).
GO analyses of encoded proteins suggested implications for the cellular/organismal protective, adaptive, and survival functions encoded by the memory genes.
Membrane-associated memory genes present another paradigm of biological relevance for the dehydration memory genes.
These genes are referred to as 'revised response' memory genes.
Thus, shared memory genes are producing more, memory genes are producing fewer transcripts, while revised-response memory genes return transcripts closer to their initial (W) levels.
Differential expression of known memory genes after conditioning.
None of the memory genes encodes a thylakoid membrane function.
These data suggest a common theme for cycling molecules in the formation of long-term memory, and suggest that like other known circadian genes, Fabp-mediated signaling is likely implicated in both sleep/wake and memory-related processes.
This study identifies some of the first genes required for remote memory, and suggests that screens of targeted mutants may be an efficient strategy to identify molecular requirements for this process.
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