Although an insidious history of episodic memory difficulty is a typical presenting symptom of Alzheimer's disease, detailed neuropsychological profiling frequently demonstrates deficits in other cognitive domains, including language.
Memory difficulties were three times more likely to be reported by subjects using a psychotropic.
To summarize the significant covariate results for subscale analyses, working memory difficulties were associated with lower scores on the social skills subscale (β = −0.005, Wald χ 58) = 6.94, P < 0.009) and on the fantasy/magical thinking subscale (β = −0.004, Wald χ 58) = 4.89, P < 0.03).
Memory difficulties are a frequent cognitive complaint of patients with chronic epilepsy.
Depressive symptoms, irritability and reduced awareness of subtle memory difficulties are also common.
Children with working memory difficulties are at high risk of academic failure.
Cognitive function items are increasingly included in quality of life measures, and complaints of concentration and memory difficulties are often reported by cancer patients.
Because working memory difficulties are increasingly recognised as a hallmark feature of specific learning difficulties (e.g. Rose, 2009), as well as slow rates of learning more generally (e.g. Gathercole & Alloway, 2008), these findings have practical implications.
Moreover, the central hypothesis of neurotoxicity as evidenced by memory difficulties (which was reported to be more prominent among those with persisting CNS symptoms) suffers from the confounding influences of responder symptomatic status, lack of reference to exposure risk, lenient statistical maneuvers with wide statistical errors, and lack of explicit supportive documentation.
Patients who report concentration and memory difficulties should be screened for clinically significant and potentially remediable mood disorder.
