Sentence examples for memory defects in from inspiring English sources
Lourenco, M. V. et al. Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models.
Isoflurane exposure leads to neuronal apoptosis, and subsequent learning and memory defects in the developing brain.
The present study was designed to investigate the ameliorative role of cilnidipine and nimodipine in immobilization stress-induced behavioral alterations and memory defects in the mice.
For 10 dae flies, all Aβ flies reached a similar level of memory defects in the male group (left panel in Figure 2D).
We have previously engineered transgenic Drosophila melanogaster strains that express human Aβ42 peptides and shown that Aβ expression promotes degeneration of the nervous system with concomitant learning and memory defects, in a dose dependent manner [22], [25].
Since adult neurogenesis is crucial for spatial memory, which is particularly vulnerable in AD, these findings suggest that AICD can exacerbate memory defects in AD by impairing adult neurogenesis.
It has been suggested that severe memory defect in an elderly person carries a poor prognosis, being related to such factors as a shortened survival time and an increased death rate.
This study represents the first example of Aβ1-42 monoclonantibody-decoratedted nanoparticle-based therapy against AD leading to complete correction of the memory defect in an experimental model of AD.
In this study, we generated a deletion mutant of magi-1 and investigated the learning and memory defect in the mutant worms.
Post-hoc Fisher's PLSD test revealed no significant difference in alternation performances between 5XFAD and BACE1+/−·5XFAD mice (p = 0.24), indicating that BACE1+/− deletion failed to improve the spatial working memory defect in 5XFAD mice at this advanced age.
Two lines that express in subsets of MB011B cell types, MB210B and MB002B, showed a memory defect in the primary screening but failed to reach statistical significance when retested with the weaker effector.
