Sentence examples for memory compartment and from inspiring English sources

Thus, we provide a link between lymphopenia and the formation of the 'virtual memory' compartment and highlight the significant changes in T cell surface phenotype that can occur in a lymphopenic environment.

In mice, the pool of CD45RA+ naïve T cells decreases due to thymic involution (Nikolich-Zugich, 2008), while the CD45RO+ memory compartment and Tregs increase with aging (Han et al., 2009).

We have shown that the BANK1 risk variants are associated with homeostatic changes in the peripheral B-cell pool that include a significant expansion of the total memory and preswitch memory compartment; and a significant decrease in naïve B cells in subjects homozygous for the BANK1 risk alleles.

For this reason, 9G4 B cells only account for 5 10%% of the naïve B cell repertoire in healthy donors, as well as in the IgM memory compartment, and these cells can be found in less than 1%% of germinal centers in tonsil biopsies [ 36, 38].

Annexin V staining was more pronounced in the memory compartment, including TCM and TTM lymphocytes, that is, the cell types that encompass the HIV-1 reservoirs (P<0.05, repeated measures ANOVA followed by the Newman Keuls post-hoc test, five donors).

These SAMHD1low cells were preferentially in the memory compartment of adult PBMCs and could not be identified within cord blood (Fig. 2a).

They are found within and in proximity to germinal centers in secondary lymphoid organs, and their memory compartment also circulates in the blood.

This increase persisted when the cells transited into the memory compartment, as frequency of LCMV-specific CD4+ and CD8+ T cells remained higher in mutant mice by 50 days after infection (Figure 4C).

As shown in the graphs below, Vav-Atg5-/ are both lymphopenic and accumulate the "virtual" memory compartment, which is identical to the phenotype observed in Vav-Atg7-/.

We therefore chose to investigate the qualitative, rather than the quantitative relationship between the pathogen environment and the diversity in the memory compartment.

Although we were unable to identify an enrichment of WASp+ B cells within the IgM+ memory compartment, the very low absolute numbers of total and IgM+ memory B cells significantly limited this analysis.