Sentence examples for memory and neuronal from inspiring English sources

Furthermore, knockout of the p62 protein alone leads to neuropathological lesions including the accumulation of hyperphosphorylated tau and neurofibrillary tangles, synaptic deficiencies with loss of working memory and neuronal apoptosis (Babu et al., 2005; Wooten et al., 2008).

Our previous study has demonstrated essential roles of presenilins in memory and neuronal survival.

The gene homologous of EGR1, zif268, Egr-1 or ZENK, together with other members of the EGR family, are consolidating as key players in short and long-term memory and neuronal plasticity in the brain.

Presenilins promote memory and neuronal survival in a γ-secretase-dependent manner, as conditional inactivation of another component of the γ-secretase complex, nicastrin, results in similar patterns of memory impairment and age-related neurodegeneration [13].

We also measured CREB, a transcriptional factor involved in memory and neuronal survival that can be activated via its phosphorylation at serine (Ser) 133 by several kinases, including ERK.

In neuronal systems CREB has been shown to regulate a wide variety of key processes including development, synaptic plasticity, memory and neuronal survival decision-making [1,2,37,38].

An overview of recent advances in our understanding of the molecular mechanisms of estrogen action is discussed in the context of designing an efficacious NeuroSERM that will activate cellular, biochemical and genomic events required for the promotion of memory function and neuronal survival.

P300 promotes a signalling mechanism that is important for long-term memory formation and neuronal survival.

Tests of these predictions will improve understanding of the coupling between memory maintenance and neuronal activity.

DHEA and its C7-oxygenated metabolites are considered neurosteroids and they play a role in the regulation of emotional responses, memory functions and neuronal excitability [24] [26].

Furthermore, Pum is also involved in the development and migration of primordial germ cells [20], [21], [22], and it may be implicated in long-term memory formation and neuronal excitability [23], [24], [25].