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Louis nevertheless possessed an excellent memory, acquired a sound knowledge of Latin and English, and took an interest in history and geography.
These results are entirely consistent with those from previous studies in which spatial information was encoded through simultaneous viewing of all object locations, suggesting that the intrinsic reference theory is not specific to a type of spatial memory acquired by the particular learning method but instead generalizes to spatial memories learned through a variety of encoding conditions.
These results imply that acquisition of the dry maze is impaired, and that reference memory acquired is less precise, in iv/iv mice.
But there still remains a possibility that the memory stored elsewhere could not be retrieved because the exactly the same neuronal connections within the PC failed to be restored for the retrieval of the memory acquired before the PC lesioning.
However, memory acquired before the surgery could not be retrieved 1 month after surgery although the procerebrum had recovered from injury by this time, consistent with the notion that the procerebrum is the storage site of odor-aversion memory, or deeply involved in the memory recall process.
This might be accomplished, for example, by enhancing the consolidation of memory acquired shortly before injections and/or by facilitating learning during subsequent training (see below).
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It is known that sleep reshapes the neural representations that subtend the memories acquired while navigating in a virtual environment.
These data indicate that post-training sleep modulates the neural substrates of the consolidation of both the spatial and contextual memories acquired during virtual navigation.
Wright & Harding (1982) [42] also demonstrated that olfactory memories acquired before bulbectomy can be retrieved after recovery, suggesting that the olfactory memory is not stored in the olfactory bulb.
This interpretation is in accordance with findings from a recent study by Dupret et al. showing that ablation of adult neurogenesis results in an impairment to flexibly express spatial memories acquired previously using either changing or constant starting positions [7].
Here, we investigated the effect of post-training sleep on the neural substrates of the consolidation of spatial and contextual memories acquired while navigating in a complex 3D, naturalistic virtual town.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com