Sentence examples for membrane transporter function from inspiring English sources

Although major advances have been made over recent years in our understanding of membrane transporter function in mammalian tissues it is also likely that many unidentified transport systems will play unique physiological roles.

Furthermore binding is directly dependent on its interaction with a highly accessible target without intervening processes (e.g. cell membrane transporter function, vessel permeability, tissue diffusion) that have the potential to confound quantitative reporting of the molecular target.

The work described in this manuscript has explored a novel strategy for gaining insight into the mechanisms of membrane transporter functioning.

Ceftriaxone treatment however did not affect transporter translation, post-translational trafficking to and from the plasma membrane and transporter function within the membrane: we were unable to detect any alteration of EAAT2 expression after 5, 10 and 15 days of treatment refuting a time dependence of expression regulation seen in the study by Chu et al. [33].

Previous findings report that the membrane transporters, which function in cellular transport processes for the maintenance and re-establishment of homeostasis in the plant cytoplasm, were induced with various forms of abiotic stress [ 37].

Supplementation of media for growth of wine yeasts with oleic acid and ergosterol can alleviate oxidative stress during must fermentation (Landolfo et al. 2010), as lipid composition of the cell membrane modulates the activity of enzymes and membrane-associated transporter functions (Avery et al. 1995; Vigh et al. 1998).

Specifically, polarographic analysis permits assessment of mitochondrial integrated respiratory capacity from electron entry into the respiratory chain through final acceptance by oxygen, in addition to coupling between oxidation and phosphorylation, as well as inner mitochondrial membrane permeability and transporter function.

By contrast, the low-affinity vacuolar iron transporter Smf3 (DMT1 in mammals), which is a homologue of the cell membrane transporter Smf1, mainly functions in iron rich conditions (Portnoy et al., 2000; Portnoy et al., 2002).

Monogenic cholestatic diseases recently identified illustrate the key role of membrane transporters in biliary function.

GadC is one of the proteins directly involved in acid resistance (membrane transporter of glutamate) rather than functioning as a regulator.

The function of SLC45A2 is still unknown, but studies from Medaka fish show that the SLC45A2 protein plays an important role in pigmentation and probably functions as a membrane transporter in melanosomes [ 53].