Sentence examples for membrane scission process from inspiring English sources
Answers to these questions are required to understand this fundamental membrane scission process.
These membrane-associated ESCRT-III polymers can delineate and generate vesicles within the lumen of MVB and participate in the membrane scission process [ 6].
Our evidence that shits1 is not perturbing outputs (at least at 25°C) raises that possibility that other membrane scission-sensitive processes, such as receptor endocytosis, may have a lower threshold for disruption than synaptic transmission.
ESCRT complexes (of which there are five) are involved in vesicle and membrane scission in many processes, including viral budding and cytokinesis, in addition to multivesicular body formation (Hanson et al., 2009; Raiborg and Stenmark, 2009).
Despite uncertainties surrounding the native structure of ESCRT-III in vivo and the mechanism by which it drives membrane scission, its function in this process is well supported by studies revealing that the role of ESCRT-III is not restricted to the ILV budding pathway.
This ability of ESCRT-III to catalyze membrane scission applies to its role in other processes as well, such as cytokinesis and viral budding.
This may be due to proton leakage during membrane scission, or some other physical aspect of the fission process.
Indeed, the membrane scission activity of ESCRT-III appears to have essential roles in cellular processes that are unrelated to transmembrane protein degradation.
The ESCRT machinery along with the AAA+ ATPase Vps4 drive membrane scission for trafficking into multivesicular bodies in the endocytic pathway and for the topologically related processes of viral budding and cytokinesis, but how they accomplish this remains unclear.
A process termed abscission severs the midbody connection, and this step appears to depend on the membrane scission activity of ESCRT-III/VPS4.
In the above-mentioned processes, the ESCRT machinery helps to bend membranes away from the cytoplasm until it executes membrane scission.
