Sentence examples for membrane receptor levels from inspiring English sources

Il-1β has diverse functions relating to its unique ability to regulate inflammation at both the nuclear and membrane receptor levels.

In contrast, there is no BG induced loss of NTR1 from the plasma membrane; in fact NTR1 plasma membrane receptor levels slightly increase with BG treatment as opposed to NT exposure (middle panels).

Where examined, however, internalization was observed to occur rapidly, with membrane receptor levels plateauing within minutes or at most one to three hours following chronic exposure to muscarinic agonists [ 84- 86].

As in previous models [ 41, 42, 50], receptors are considered pre-dimerized and binding of the ligand is a reversible single-step reaction; in addition, internalization and receptor insertion are balanced to keep plasma membrane receptor levels constant.

These apparently disparate effects are dependent on context, including state of differentiation, presence of other growth factors or cytokines, matrix molecules, additional proximal cell populations, and membrane receptor levels.

For many cell surface receptors, e.g. EGFR, plasma membrane receptor levels and the consequent signalling response can be regulated by sorting decisions made at the early endosome, for example between recycling of the receptor back to the plasma membrane, or degradation in the lysosome (33).

Since plasma cell surface expression of the transfected WT GnRHR was relatively low in this tumor cell line, the over-expressed mutant form, GnRHR-DesK191 was also employed to explore the effect of increased cell surface membrane-expressed receptor levels on several cell markers associated with locomotion dynamics.

Down-regulation of NF-κB could therefore result in a decrease in crucial anti-apoptotic influences both at the mitochondrial and the membrane death receptors levels.

Very low and unchanging gene expression levels of calcium sensing receptor (CaSR), the membrane receptor which senses extracellular calcium levels, were detected by qPCR and SuperSAGE (not shown).

Monocyte membrane receptor analysis revealed increased expression levels of CD11b (integrin αM β2), CD14 and CD31 (platelet endothelial cell adhesion molecule-1), and the chemokine receptors CCR5 and CXCR4, but not of CCR2.

There are numerous possible interactions between the chemicals based on alterations in systemic disposition, biotransformation, or toxicodynamic interactions at the membrane, cellular, or receptor level.