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The abundant polymerization of actin filaments beneath EPEC results in the bacteria rising off the natural surface of the cell on actin-rich membrane protrusions called "pedestals", which are hallmarks of the disease [3], [4].
For example, in bacteria they form 2-dimensional crystalline membrane patches, whereas invertebrate opsins occupy cellular membrane protrusions called microvilli of rhabdomeric photoreceptor cells.
Collagen fibril assembly in embryonic development occurs in recesses of the plasma membrane [ 29,30 ], and newly formed collagen fibrils occur in plasma membrane protrusions called fibripositors [ 26].
Invading cancer cells form filamentous actin (F-actin -based membrane protrusions called invadopodia, whose extracellular matrix (ECM) degrading activity allows them to invade through basement membranes and migrate toward blood vessels [ 1].
These synapses are not formed on the cell bodies of the muscles but instead onto the dendritic spine-like postsynaptic membrane protrusions called muscle arms (White et al., 1986; Leung et al., 1999; Collins and Koelle, 2012).
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In humans, bones have protrusions called condyles that help form joints.
In mammalian neurons, excitatory synaptic transmission occurs primarily at specialized, actin-rich protrusions called dendritic spines.
Human auditory transduction occurs in sensory hair cells with a staircase-like arrangement of apical protrusions called stereocilia.
Third, Hh may be transferred by long cellular protrusions called cytonemes (Ramírez-Weber and Kornberg, 1999).
These protrusions, called streamers, form within two minutes of antibody exposure.
In 2011, a new kind of thin extracellular protrusions, called a nanopodium, was reported.
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