Sentence examples for membrane proteins represent from inspiring English sources
From G protein-coupled receptors to ion channels, membrane proteins represent over half of known drug targets.
Membrane proteins represent 20 30% of total proteins in all species [1] and up to 60% of pharmaceutical targets [2].
Cell membrane proteins represent the largest fraction of this distinctive group, with 14 out of 39 annotated as cellular envelope (see Table S5).
Membrane proteins represent a potentially important source of putative cancer biomarkers but are currently understudied due to their low solubility.
Therefore, membrane proteins represent a gold mine of targets that must be screened in order to fully exploit their rich therapeutic potential.
Membrane proteins represent between 20 and 30% of the proteomes of most organisms [ 1] and more than 40% of drug targets [ 2] and yet very few structures of these molecules have been solved by X-ray crystallography or NMR.
Therefore investigation of membrane proteins is a demanding undertaking and generation of mAbs against membrane proteins represents a difficult task.
Three SAPs are putative membrane proteins representing a new protein family of membrane receptors connecting the cytoskeleton and the ECM analogous to animal integrins.
Thus, monitoring ATPase activity in cell membrane preparations, or purified membrane proteins, represents a method of identifying those compounds that interact with the drug efflux transporters.
This integral membrane protein represents an important part of the tight junctions, which seal and protect the blood brain barrier against paracellular diffusion of solutes to the brain parenchyme and are therefore responsible for the high resistance and low permeability between cerebral capillary endothelial cells.
The secretory nature of the mantle tissue requires a number of membrane transport proteins, represented in our limited identifications by a component of a voltage gated potassium channel complex, a V-type ATP synthase, which may transport solutes and lower pH in organelles, prosaposin and the endoplasmic reticulum transport protein SEC61 α sub-unit.
