Thus, monitoring regulation of mouse K2P2.1 (TREK-1) by changes in membrane potential presented a facile tool to assay regulation of channel activity by multiple commands converging on Ct.
A reduction in mitochondrial membrane potential is present in various genetic models of HD, as well as in lymphoblasts isolated from HD patients (23– 23).
mHtt interacts with mitochondria, and a reduction in mitochondrial membrane potential is present in various genetic models of HD, as well as in lymphoblasts isolated from HD patients (11, 12).
Mitochondrial membrane potential is presented as relative fluorescence units, RFUs.
In lipid bilayers where both mechanical membrane tension and electrostatic membrane potential may be present, such an occluded conformation may or may not be thermodynamically stable.
Perhaps any membrane potential that is present, is insufficient to support the function of a TIM23 translocase.
JC-1 accumulates in cells when a mitochondrial membrane potential (MMP) is present (resting cells are hyperpolarized) and forms aggregates which emit red fluorescence.
Whether or not the impact of STAT3 on MPTP opening is due to changes in the mitochondrial membrane potential is unknown at present.
where g k is a constant and τ L = C k g k is the characteristic time for membrane potential decay when no current is present ("leak term").
Consistent with this hypothesis, LiCl-treated neurons present higher mitochondrial membrane potential than untreated cells (Figure 4D).
