Sentence examples for membrane potential observed from inspiring English sources
DOI: http://dx.doi.org/10.7554/eLife.00012.004 The small changes in membrane potential observed here and in other studies raise the issue of whether the observed plasticity is sufficient to modify spiking responses in the postsynaptic neuron.
Here, we will consider an anomalous type of bursting in which the silent, interburst interval occurs at more depolarized potentials than the average membrane potential observed during the interspike intervals within a burst.
Moreover, the increased membrane potential observed with α-ketoglutarate + malate in xav, as discussed above, may also contribute to the increased ROS production.
Therefore it has been suggested that the loss of mitochondrial membrane potential observed following PINK1 silencing will have a significant effect on ATP production, and thus cellular function and survival.
Aflibercept (figure 2C): There were statistically significant decreases in mitochondrial membrane potential observed at 10× and 2× clinical doses in cells treated with aflibercept.
The dissipation of mitochondrial membrane potential observed by flow cytometry and the expression of activated caspases with the cleaved poly (ADP-ribose) polymerase under immunoblotting analysis indicated that Tan IIA-induced apoptosis in KB cells was mediated through the mitochondria-dependent caspase pathway.
On each box, the central mark is the median, the edges of the box are the 25th and 75th percentiles and the whiskers extend to the most extreme membrane potentials observed.
Resting membrane potentials (observed before and after TTX application) showed regular cycling between −37 and −68 mV.
The decrease in membrane dipole potential observed in this study could therefore stimulate the indirect activation of signaling pathways by indirectly instigating a conformational change in transmembrane receptor structure.
These modeling results show that the membrane potential changes observed in vivo are broader than those observed in vitro and that the broader time course can be explained by variably-timed inputs (but see Lin et al., 2003; Froemke et al., 2005; Zhang et al., 2009 for alternative sources of broader STDP windows).
It is worth noting here that the mitochondrial swelling observed in these cells were associated with decreased mitochondrial membrane potential as observed by FACS analysis (Supplementary Figure S5).
