Sentence examples for membrane potential increasing from inspiring English sources

We think that during gametogenesis, fertilization and embryo development, mitochondria undergo selection for different traits (e.g. replication, membrane potential), increasing the probability of the transmission of functional organelles.

In free-running simulations of membrane potential, increasing Kir7.1 channel density (within the range measured in our experimental data) hyperpolarized resting membrane potential and decreased calcium entry during the action potential (Fig 3).

During phase 0 of an action potential fast Na+-influx leads to a steep increase of the membrane potential increasing the probability that the voltage dependent L-type Ca2+ channels will open.

For example, smooth muscle relaxation can occur by agents that reduce myoplasmic Ca2+ by inducing hyperpolarization, reducing Ca2+ influx without changes in membrane potential, increasing Ca2+ efflux, or by reducing Ca2+ release from the internal store.

CCI injuries also resulted in an immediate decrease in ATP concentrations, decreased mitochondrial membrane potential, increased mitochondrial permeability transition and increased ROS production in isolated cortical synaptosomes (Sullivan et al., 1998; Sullivan et al., 1999).

Methods for cytotoxicity analysis showed that PEG-AuNP did not affect cell viability, but intracellular ATP levels and mitochondrial membrane potential increased.

Importantly, myocardial and mitochondrial ultrastructural abnormalities were more pronounced in HF-fed offspring with prenatal fat exposure, shown as loss of mitochondrial density and membrane potential, increased ROS generation and apoptosis.

In addition to morphomechanical changes, hDMPK A expression induces physiological changes like loss of mitochondrial membrane potential, increased autophagy activity, and leakage of cytochrome c from the mitochondrial intermembrane space accompanied by apoptosis.

The variance of the membrane potential increased significantly after application of ACSF1 (Fig. 4B, n = 11, p<0.05 paired t-test) but showed no statistically significant difference from the control values after adding synaptic blockers (n = 10, p>0.5 paired t-test).

Other isomalabaricane triterpenoids were found to induce reactive oxygen species (ROS), decrease mitochondrial membrane potential, increase the levels of Bax and cytochrome c, decrease the levels of Bcl-2 and mediate a caspases-3 apoptotic pathway, but the molecular mechanisms responsible for triterpenoids-induced cell death have not been elucidated yet[5].

These changes include a depolarized resting membrane potential, increased depolarizing sag potential and increased action potential firing rates, which are all indications of hyperexcitability.