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Membrane potential depolarization causes alterations in neuron arrangement and connectivity in cocultures.
K2P channels were blocked in open and closed states, resulting in resting membrane potential depolarization.
Outer mitochondrial membrane permeabilization during apoptosis triggers caspase-independent mitochondrial and caspase-dependent plasma membrane potential depolarization: a single-cell analysis.
TQ also inhibited the mitochondrial membrane potential depolarization and reactive oxygen species generation caused by Aβ1 42.
Despite its higher antibacterial activity, IsCT-p was much less effective at inducing dye leakage in the negatively charged liposome mimicking bacterial membrane and induced no or little membrane potential depolarization of Staphylococcus aureus.
The subsequent opening of transient receptor potential (TRP) ion channels effectively lowers the cell's membrane potential (depolarization), inducing an electric current through the cell (Hardie 2001).
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In glomerulosa, delayed inactivation is inferred to increase the period of membrane potential depolarizations.
To substantiate our finding that activation of the SK2 channel induces membrane potential depolarizations in neuronal mitochondria, we isolated mitochondria from mouse brain synaptosomes and from total brain and analyzed ΔΨm here by Rhodamine 123 fluorescence.
In this work, human mesenchymal stem cells (hMSCs) from five donors were evaluated for their response to membrane potential (Vmem) depolarization.
In 11 cells that presented robust tuning, efferent stimulation eliminated the typical damped oscillation in the membrane potential following depolarization (Fig. 3A).
Membrane potential disruption (depolarization) was achieved by two classic methods: addition of high concentrations of extracellular K+ (high [K+]out), or addition of the Na+/K+ ATPase blocker ouabain.
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