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Membrane potential also continuously decreased with increase of the pressure until 400 MPa [ 20, 22].
The membrane potential also decayed slowly (2.62 ± 1.84 s; best fit single exponential).
Depolarization of the membrane potential also occurs during place field traversal in freely moving rats (Lee et al. 2008).
Furthermore, in yeast mitochondrial dysfunction (as measured by impaired mitochondrial membrane potential) also induces mitophagy, which is followed by cell death (32).
The differences in resting membrane potential also may reflect an indirect regulation of ion diffusion, which would be a useful area for future inquiry.
The muscle relative refractory period (RRP) increases and supernormality (SN) decreases in ischaemia, suggesting that these measures may be indicators of membrane potential also in the muscle [ 2].
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The mitochondrial membrane potential is also reduced and negatively affects hypoxic cells [75].
Morphological changes of cell through alteration of nuclear content and mitochondrial membrane potential were also examined using Hoechst and JC1 stains under fluorescence microscopy, respectively.
In cells which have this synaptic potential, part of the resting membrane potential is also maintained by an electrogenic sodium pump.
Three analogues (3, 4 and 6) were identified that exhibited significantly improved effects on mitochondrial oxygen consumption and mitochondrial membrane potential, and also conferred significant cytoprotection on cultured mammalian cells in which glutathione had been depleted by treatment with diethyl maleate.
However, at this concentration the plasma membrane potential is also affected by this uncoupling agent (results not shown and [22]).
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