Sentence examples for membrane of target from inspiring English sources

Physical delivery methods act to overcome the extracellular barriers to gene delivery and/or to temporarily disrupt the membrane of target cells, allowing DNA entry.

Somatostatin-14 (SS14) is a native peptide hormone exerting a variety of physiological actions in the brain and in peripheral tissues after binding to high affinity receptors on the cell membrane of target cells [1 3].

These engineered erythrocytes are able to fuse with the cytoplasmatic membrane of target cells in a very short time and release the magnetic nanoparticles and therapeutic compound inside these cells.

Thus, in one pathway, the lethal activity of the toxin may be a direct effect of the toxin forming oligomeric pores in the plasma membrane of target cells, leading to depolarization of the cell's electrochemical gradient, disruption of ion homeostasis, and cell death.

MAC (C5b-9) is generated upon complement activation and inserted into the membrane of target cells.

We hypothesized they might display a good bioaffinity and readily fused with the membrane of target cells.

Moreover, synaptic connections with other neurons are made at precise locations on the cell membranes of target neurons.

These neuropeptides are produced in the corpora cardiaca and perform their hormonal function by interacting with specific G protein-coupled receptors (GPCRs) at the cell membranes of target tissues, mainly the fat body.

CTL and NK granules contain numerous granzymes as well as a poreforming protein, perforin, which oligomerizes in the membranes of target cells to permit entry of the granzymes.

Chemokines work by binding to specific G-protein-coupled receptors on plasma membranes of target cells.

Moreover, chemokines are small chemo-attractant cytokines that bind to specific G-protein-coupled transmembrane receptors present on the plasma membranes of target cells.