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Disruption of the sarcoglycan complex, through primary gene mutations in dystrophin or sarcoglycan subunits, produces membrane instability and muscular dystrophy.
The paper discusses membrane instability phenomena by a Fourier-related double scale approach that was introduced recently.
The intracellular redox status and the closely associated membrane modifications seemed to be related to membrane instability, loss of surface area through vesiculation, echinocytosis and stomatocytosis.
The average size and lifetime of the defects might be related to the degree of membrane instability and membrane stress.
However, our results show that the dye efflux characteristics are consistent with bilayer defects caused by membrane instability.
However, these events were very difficult to reproduce, partly because the conditions required for these events also induce membrane instability.
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Regarding the lysis (rupture) of cellular membrane of E. coli O157 H7 on hydrophilic substrates functionalized with positively charged amines (Figs 4f and S1), the membrane instabilities induced by electrostatic interactions and interactions can be considered.
A criterion for membrane shape instability is derived from a linear stability analysis.
Furthermore, it was found that Danggui extract can block Ang II-induced mitochondria membrane potential instability and cytochrome c release.
In conclusion, we have developed a C. elegans model that recapitulates post-transcriptional ΔF508-dependent membrane protein instability.
Recordings in which the input resistance fluctuated more than 20% during the experiment, indicating leakiness of the membrane and instability of the whole-cell patch-clamp recording, were discarded.
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