Sentence examples for membrane fusion has from inspiring English sources

The mechanism of influenza hemagglutinin (HA) mediated membrane fusion has been intensively studied for over 20 years after the bromelain-released ectodomain of HA at neutral pH was first crystallized.

Membrane fusion has also been found in every other animal studied, including mammals.

Intracellular membrane fusion has been mimicked in vitro using a mix of 17 purified proteins and lipid bilayers.

Moreover, the allosteric mode of MPER during membrane fusion has not been demonstrated.

ST-294, a potent inhibitor of NWA membrane fusion has also demonstrated activity in a newborn mouse TCRV infection model [4].

The ability of the Ebola peptide to induce membrane fusion has been related with the presence of phosphatidilinositol in the host cell membrane and Ca2+ during this process [13], [14].

HA mutants with elevated pH values for membrane fusion have been mapped exclusively to (a) HA1 HA1 interfaces, (b) HA1 HA2 interfaces, (c) the fusion peptide and its surrounding region, and (d) the region around the B-loop, suggesting that these regions are involved in structural rearrangements of HA in the transition from the prefusion state to the postfusion state.

Mutations that affect the pH threshold for membrane fusion have also been mapped to this hydrophobic pocket [12], [13].

First, studies of homotypic vacuolar membrane fusion have suggested that the V0 sectors on opposing membranes can form a proteolipid fusion pore and that radial dissociation and expansion of V0 sectors results in membrane fusion [13], [14].

Putative mechanisms by which class I viral fusion proteins achieve membrane fusion have been proposed [1], [4], [17] [19], but complete structural evidence for the role of intermediate structures in these mechanisms has yet to be obtained.

Determinants of cellular tropism and interaction with the target cell are within the S1 domain, while mediators of membrane fusion have been identified within the S2 domain.