Sentence examples for membrane fluidity alteration from inspiring English sources

Numerous studies have shown the interaction of doxorubicin with membranes, particularly cardiolipin (CL), causing membrane fluidity alteration and enzyme activity deficiency [ 2– 4].

In addition, lipid peroxidation leads to a reduction in membrane fluidity, alteration of membrane-bounded protein, receptors, and ion channels, and generation of Aβ that induces more oxidative stress and calcium influx that induces glutamate excitotoxicity and cell death [ 50, 51].

As a result of these changes, significant alterations in the biophysical properties of liver membranes are observed, such as altered membrane fluidity and morphological alterations.

29 It is possible that alterations in the membrane fluidity could alter bacterial adhesion and translocation through epithelial cells.

Since the tendency of persistent mycobacteria to store fatty acids selectively in neutral lipids appears to be a consequence of an extended intracellular habitat, it is tempting to postulate that this change will result in an alteration of membrane fluidity in response to the intracellular stress as suggested for Rhodococcus (Alvarez and Steinbuchel, 2002).

The alteration of membrane fluidity, by both psychrophilic and thermophilic bacteria, is an example of structural adaptation.

Liposomes increased vinblastine accumulation in resistant human lymphoblastic leukemic cell CEM/VLB100 even when the drug was co-administered in free form rather than incorporated within the liposomes, probably due to amalgamation of lipidic components into cell membrane lipids and subsequent alteration in membrane fluidity (Warren et al. 1992).

Therefore, the antimalarial activity of MeSter would directly depend on a profound alteration of membrane fluidity.

Alteration of membrane fluidity by ceramide has also been shown to affect permeability of IEC [52] and the function of diverse ion channels [53], [54], which may also contribute to extensive loss of fluids and increase of IEC apoptosis in IBD.

High temperature causes modifications in membrane functions, associated with alteration of membrane fluidity.

In S. cerevisiae, erg6 mutants showed alteration in membrane fluidity and permeability [ 41, 42].