Sentence examples for membrane fission process from inspiring English sources

Our study in mammalian cells provides another mechanistic insight into the site of action of P4-ATPases: PS flipped by ATP8A1 to the cytosolic leaflet recruits a membrane fission protein EHD1 that has an ability to bind PS, thereby regulating the membrane fission process.

ITSN is a scaffold and regulator of the general endocytic machinery; through its strategic location at the neck region of caveolae and ability to bind simultaneously more dynamin-2 molecules, ITSN recruits dynamin-2 and regulates its GTPase and oligomerization activity at the neck region of caveolae, mediating the membrane fission process and caveolae internalization.

The sister cells then re-spread and separate in the mid-body by removal of cytoskeletal structures from the intercellular bridge, constriction of the cell cortex (furrow ingression), and plasma membrane fission (the process of abscission) [ 34, 35].

In 2005 it was published that CtBP3/BARS drives membrane fission in processes where dynamin is not involved (Bonazzi et al. 2005).

These results indicate that Pex11pβ-enriched subregions on the peroxisomal membrane form before the fission process is initiated.

Formation of new membrane compartments and maintenance of complex organelles require division and disconnection of cellular membranes, a process termed membrane fission.

MTP18 was recently described as a transcriptionally regulated target of phosphatidylinositol 3-kinase signalling that is localized within mitochondrial membranes and is thought to provide the limiting step during the fission process of the inner membrane, in parallel to the action of FIS1 at the outer membrane [28], [29].

One possible explanation for the enlarged endosome phenotype associated with Ub-EEA1 is that activation of EEA1 by ubiquitination may not only induce endosome fusion, but also block an endosome fission process required for recycling of certain membrane receptors such as the transferrin receptor to the plasma membrane.

The mechanistic background for these predictions comes from a qualitative consideration of the mechanical stability of a funnel-like membrane neck, an unavoidable intermediate stage of the fission process.

This may be due to proton leakage during membrane scission, or some other physical aspect of the fission process.

These observations can be explained by the fission process requiring considerable force/strain being imposed on membrane.