Immunofluorescence analysis shows that H2O2 up-regulated the membrane expression of wild-type RAGE.
FAM2-LV induced high-level and functional membrane expression of the transgenic antibody in a nonsecretory B-cell line.
Here we design and evaluate a ligand-receptor system based on the tumor cell membrane expression of GRP78.
The surface membrane expression of the sialoglycoconjugate structure in each of the cancer cell lines was the key to these differences.
In particular, the m152/gp40 glycoprotein of MCMV lowers the membrane expression of RAE-1.
Furthermore, a preferential plasma membrane expression of Tensin3 was correlated with greater survival.
FACS analysis also confirmed membrane expression of all 3 gD-tagged proteins (Supplemental Fig. S2).
Moreover, surface membrane expression of Kv4.2 channels is regulated in an activity- and NMDAR-dependent manner [12].
However, when 293T cells were transfected with CD40L or CD40Lmut, surface membrane expression of CD40L was detectable (not shown).
N-glycosylation enhances plasma membrane expression of Xenopus ClC-5, but it is not required for its endosomal localization [39].
However, plasma membrane expression of ClC-7 in HEK-cells was reported by Kajiya and coworkers [32].
