Sentence examples for membrane entry of from inspiring English sources

Attached to the host cell membrane, entry of the viral nucleic acid was thought to occur one of two ways: via the formation of a pore in the plasma membrane through which the RNA is then "injected" into the host cell cytoplasm, or that the virus is taken up by receptor-mediated endocytosis.

(C ) HEK293T cells were transfected with siRNA against FIP200 followed by analysis of membrane entry of IL-1β as shown in (A ).

However, in this condition, the secretion and membrane entry of IL-1β were not affected indicating that this key chaperone for CMA is not involved in the secretion of IL-1β.

This proves that a staple as short as 24 aa is able to efficiently link the functional modules together allowing the neurotoxin to accomplish its sophisticated functions: binding to neuronal membranes, entry of the botulinum enzyme into cytosol, and a highly specific proteolysis of its intraneuronal target.

For the sequential reaction platform, the reaction sequence was physically separated into two discrete steps with the first (UDP-Glc formation, reaction 1) occurring on the top face of the membrane (entry) and the second (aglycon glucosylation, reaction 2) on the bottom face (exit).

The Ca2+ absorptive system [ 3] is comprised of an apical membrane entry pathway (the Ca2+-selective TRPV5 and/or TRPV6 channel), a cytosolic Ca2+ buffer protein (calbindin-D9K and calbindin-D28K), and basolateral Ca2+ exit pathways (sodium-calcium exchangers (NCX) and plasma membrane Ca2+-ATPases (PMCA)).

The rate of occurrences and expected number of simple TM helices are computed for 15 sets of UniProt-derived membrane entries grouped by the number of TM helices they contain.

Fusion of the endosome and virus membranes and entry of the viral capsid into the host cell cytoplasm then requires the acidification of the environmental pH [49], [50], [51].

In particular, we have demonstrated for the first time that colistin or LL-37 permeabilization of Gram-negative outer membranes facilitates entry of the large AZM molecule.

Although the mechanism of islet basement membrane damage allowing entry of leucocytes into the intra-islet cell mass has yet to be elucidated, the islet basement membrane components identified here, and particularly the HSPG perlecan, which is known to act as a barrier to cell invasion, suggest that specialised degradative enzymes may be involved.

Secramine A decreased the proportion of MPA-induced necrotic cell death in both the B cell line Dab-1 (40 to 50% inhibition) and in the T cell line Jurkat (40% inhibition) (Figure 2A) as assessed by the measurements of the cell morphology (flow cytometry analysis using FSC and SSC parameters, see [15]) or the plasma membrane permeability (cell entry of propidium iodide).