Sentence examples for membrane docking of from inspiring English sources

As membrane docking of myosin motors is known to be controlled by Rab proteins [10], [39], [40], we next investigated by an additional proteomics screen the recruitment of small GTPases to the peroxisomal membrane focusing on membrane-associated proteins with Mr between 15 and 30 kDa.

Talpid3 participates in the earliest stages of ciliation, including centriolar satellite dispersal and plasma membrane docking of the basal body (Davey et al., 2014; Kobayashi et al., 2014).

Activation of AKT requires the generation of phosphatidylinositol-3,4,5-triphosphate (PIP3) by phosphatidylinositol 3-kinase (PI3K), together with membrane docking of AKT and dual site phosphorylation of AKT by phosphoinositide-dependent kinase-1 (PDK1) and mTOR [ 25][ 26].

Together with upstream signals, this complex promotes the formation and membrane docking of the class III phosphatidylinositol 3 (PtdIns3 -kinase (PtdIns3 -kinaseonsisting of ATG14 (ATG14L/Barkor), the Atg6 homologue BECN1 (Beclin1), VPI3K (PIK3complex VPS15 (p150) for phosphatidylinositol 3-phosphate (PI3P) produconsistingra and ofsumi, 2011).

In addition, analysis of DCV dynamics in our live cell imaging experiments and intra-synaptic localization on electron micrographs of CAPS DKO neurons revealed that CAPS-1 deletion does not affect DCV trafficking along microtubules, synaptic accumulation and membrane docking of DCVs.

Neurotransmission is a complicated process which involves multiple steps: synthesis and storage of neurotransmitter in synaptic vesicles, transmission of synaptic vesicles towards presynaptic density membrane, docking of synaptic vesicles to presynaptic membrane, release of neurotransmitter, reuptake of excessive neurotransmitters, and recycling of synaptic vesicles [ 3].

The proposed membrane docking role of helix I remains attractive to us.

For cytoplasmic tTG, targeting cargo protein to endosomal membranes occurs via its interaction with a subset of phosphoinsitides, like in the case of FGF2 [9], although spatial specificity of membrane docking sites (inner leaflet of plasma membrane versus endosomal membrane) are different.

The remarkable segregation of membrane docking and fusion events as well as the extended surface area where both processes take place around the acrosome reaction makes sperm suitable as model for studying ultrastructural and biochemical aspects of exocytosis.

Separation of function for two ancient domains (Rab-interacting domain [ Rph3al] and C2 domains [ Doc2b]) in a single gene of the rabphilin type may have occurred, possibly to allow hormone regulation of membrane docking and fusion.

The myotoxic mechanism for PLA2-like toxins has been proposed recently to be initiated by an allosteric change induced by a fatty acid binding to the protein, leading to the alignment of the membrane docking site (MDoS) and membrane disrupting site (MDiS).