The majority of BAX is found in the cytosol, but, upon initiation of apoptotic signalling, BAX inserts into the outer mitochondrial membrane and aids in opening of the mitochondrial voltage-dependent anion channels and plays a role in mitochondrial outer membrane permeabilization.
Mast cells reside in connective tissues and mucous membranes and aid in wound healing and also in defending against pathogens.
The observed hemolytic activities of pH sensitive polymers show a great potential to disrupt endosomal membranes and aid endosomal escape.
Together, oligomerization and conformational change can permit formation of pores that permeabilize membranes and aid processes such as bacterial pathogenesis, for example, through the transport of toxic proteinaceous agents (Tweten, 2005; Aroian and van der Goot, 2007).
E-cadherin, a CAM upregulated in LEC was previously shown to anchor the SC to the basement membrane and thus aid in SC maintenance [ 59] and prevent aging of SC [ 60].
Finally, the influx of Ca2+ is modulated by potassium efflux through the outwardly rectifying Kv1.3 and KCa channels that generates negative membrane potential and aids Ca2+ influx through the CRAC channel.
Several simplified membrane models featuring coexisting liquid disordered (Ld) and ordered (Lo) lipid phases have been developed to mimic the heterogeneous organization of cellular membranes, and thus, aid our understanding of the nature and functional role of ordered lipid protein nanodomains, termed "rafts".
In cases in which an allergic reaction is not the underlying cause of the condition, it may be necessary to insert a tiny plastic tube through the membrane to aid in reestablishing normal ventilation of the middle-ear cavity.
Alternatively, they may control the ratio of respiratory chain complexes in the membrane, or aid their long-term stability.
In addition to moving proteins to the plasma membrane, it has been hypothesized that exocytosis in the spine could provide additional membrane to aid spine expansion.
