In Arabidopsis, the HAT group contains 12 members divided into four classes based on sequence homology and mode of action: GNAT (Gcn5-related N-acetyltransferase), p300/CBP, TAFII250 and MYST (MOZ, YbF2, Sas2, Tip60-like) families [ 5, 6].
The Pax transcription family comprises 9 members divided into 4 groups based on the specific assembly of 3 structural domains; the highly conserved 128 amino acid DNA binding paired domain, the octapeptide and a complete or residual DNA interacting homeodomain.
In humans, there are currently 11 family members divided into three subgroups depending on the presence of single or multiple 'cystatin' domains and the presence or absence of a signal sequence.
In humans, MMPs are represented by 23 members divided into two groups based on their localization (secreted or membrane-bound) or in five groups based on their domain organization and their substrate preference (collagenases, gelatinases, stromelysins, matrilysins, and membrane-type) [ 3, 17].
Studies over the past several years have indicated that DOCK180/DOCK1 is the prototype of a superfamily of at least 11 homologous members divided into 4 subfamilies based on conservation in the DHR1/CZH1 and DHR2/CZH2 domains as well as their specificity towards Rac1 or Cdc42 [ 149, 150].
The first round of debate closed on July 12 with members divided into a series of camps.
At the June meeting, members were divided on the outlook for higher prices.
House members are divided on the best way to proceed.
And ASEAN members remain divided on whether the Rohiningya issue should be approached from a preventative diplomacy standpoint.
Focus group discussions with community members were divided on how HPV vaccination might be integrated with other services.
