Exact(1)
Yuasa et al. reported that mRNA levels of PACE4 (paired basic amino-acid-cleaving enzyme 4), a member of PCs family, increased significantly during myogenesis, whereas the expression of furin and PC6 remained unchanged, highlighting a role of PACE4 in myoblast fusion.
Similar(59)
Members of Pc Dibell's family could be seen weeping as the funeral procession arrived at the crematorium, near Clacton.
Mr Barker-McCardle said members of PC Dibell's family were also in the police force.
To test this hypothesis, we first synthesized several aromatic enediyne derivatives [44] and examined in vitro their effects on proteolytic activities of three key members of PC-family enzymes namely furin, PC5 and PC7.
Previously, members of PC-family namely: Furin, PC1/3, PC2, PC4, PACE4, PC5/6 and PC7 have been reported to be involved in the processing of various substrates at basic residues within the general motif (K/R - X n- K/R)↓ where n = 0, 2, 4 or 6 and X is any amino acid except Cys, [9]-[12].
Can the prince really be a member of the PC brigade?
As a diversity executive with Channel 4 (often viewed as a member of the PC brigade) I realise I too will have my head bitten off for writing that last sentence.
But if being a member of the PC police means not being an out-of-touch asshole, then I'll proudly rock that badge.
Several lines of evidence suggest that furin, the predominant member of the PC family, is indeed a target receptor.
Purification and characterization of this complex revealed a number of other PRC1 components, notably the Psc homolog BMI1 and both Sce proteins (RING1 and RING2), but no other member of the Pc family was reported to be present.
PACE4, a member of the PC family, activates membrane type MMPs (MT-MMPs).
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