Ai Feedback
Exact(12)
This may directly reflect the substantial increase of tumour infiltrates in comparison to residual lymphoid tissue, rendering the tissue type similar to primary melanoma rather than lymphatic tissue.
Another notable difference is skin cancer, which is more frequent in Western countries and usually presents as melanoma rather than squamous or basal cell carcinoma.
The gene expression results and studies on melanoma cell growth have provided provocative evidence that the P53 pathway in melanoma rather than acting as a tumour suppressor, may promote melanoma proliferation and progression.
Moreover, the fact that inhibition of P53 resulted in decreased proliferation in melanoma suggests that the altered functional activity of P53 may promote tumour development and progression in melanoma, rather than suppress it.
However, MDA-MB-435 has now been shown to be derived from a melanoma rather than a breast cancer, thus reducing the number of available models for studying metastasis from human breast tumours [ 31].
A UK primary care population has been shown to be more concerned about bleeding, oozing and crusting as symptoms of melanoma, rather than changes in shape or colour in pre-existing moles [ 28], compared with a similar Australian population who were better informed about the importance of change in a pre-existing lesion [ 29].
Similar(48)
Most of the previous reports on mucosal melanomas are focused on head and neck melanomas rather than melanomas arising from mucosal membrane at various anatomic sites[ 3, 14- 16].
In both datasets, methylation levels spanned a continuous gradient from unmethylated melanomas to fully methylated melanomas, rather than forming a distinctive CIMP group (Additional file 1: Figure S2).
Thus, metabolite distributions apparently mirror the similarity in vascularity of MF and EE melanomas rather than reflecting intrinsic properties with regard to tumour growth rates or susceptibility to radiation.
Although in most cases the target antigen could not be identified, the failure to lyse normal patient cells suggested that melanoma-specific or melanoma-associated rather than minor histocompatibility antigens were common targets of clones isolated from normal donors.
However, our results show upregulation by miR-124 in melanoma cells, rather than downregulation.
Related(1)
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com