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This lack of effect of acupuncture is consistent with findings of a recent systematic review of acupuncture for all OA; the review showed that, while there were statistically significant benefits in sham-controlled trials, the benefits were small, did not meet predefined thresholds for clinical relevance, and were possibly due at least partially to placebo effects from incomplete blinding [ 55].
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In this study, there was a progressive increase in the likelihood that treatment met predefined thresholds for response and remission with increasing time on atomoxetine.
NIHR noncommercial partners are organisations that meet predefined conditions in their funding processes.
In our study, baseline illness severity substantially influenced the time to meet predefined measures of improvement.
Research nurses had to meet predefined reproducibility criteria to be permitted to carry out study scans.
All fit indices met the predefined thresholds demonstrating that the 4 items contribute to a total measure of HLPC (unidimensionality).
Tumours are often detected manually by a radiologist or with computer-aided detection (CAD) systems, which utilise areas of enhancement that meet a predefined threshold.
Dose-escalated wPTX in patients with pretreated AGC met our predefined threshold of primary end point, OS (P<0.3); however, it did not show a significantly longer OS.
This study met our predefined threshold of primary end point, OS (P<0.3); however, it did not show a significantly longer OS with dose escalation.
With regards to diabetes screening, 54 participants (23%) and 27 participants (8%) in the home-based screening and community-based screening, respectively, met the predefined threshold requiring confirmatory blood sugar testing.
In conclusion, dose-escalated wPTX in patients with pretreated AGC met our predefined threshold of primary end point, OS (P<0.3); however, it did not show a significantly longer OS.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com