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Most of the adrenal radioactivity was located in the medulla with a little found in the renal cortex region).
Tissular damage prevailed in the outer medulla with a maximal expression at D6 (paucicellular tubular epithelium, intratubular casts).
The CD3+ T cells were present in the cortex and medulla with a high density at the cortex‐medulla boundary.
Plasma and CSF lactate were elevated at 11.66 and 5.56 mmol/l, respectively, and cranial MRI scan demonstrated symmetrical abnormal signal in the cerebral peduncles, dorsal pons and upper medulla, with a lactate peak clearly visible on magnetic resonance spectroscopy.
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Ovaries develop from the growing cortex, while testes develop from the medulla with an apparent antagonism between the two processes [ 5].
It has been suggested that feedback of vasoactive stimuli to juxtamedullary resistance vessels may provide the medulla with an intrinsic feedback loop, which could allow the medulla to control its own perfusion (Pallone & Silldorff 2001).
The dilated tubules were mainly located in the inner cortex and in the outer medulla, with an increase in the median diameter of the transverse tubule and an increase in the coefficient of variation.
As such, a TM sprayer was used to deposit multiple 2,5-DHB layers, followed by MALDI-TOF/TOF MS. Figure 1a shows a H & E stain for one of the four MALDI profiling sections, with the major histological regions, cortex, medulla, and pelvis annotated, and the border between the cortex and medulla indicated with a red dotted line [ 25].
Immunohistochemical analyses were performed in the cerebellum, frontal lobe and medulla oblongata with a mix of mAb F89/160.1.5 and 2G11.
The bovine BSE sample was from a clinical suspect case that was positive by statutory diagnostic methods (histopathological examination of medulla (obex) with a typical vacuolar distribution pattern and WB for PrPres using the Prionics®-Check WESTERN).
There is a loss of normal tissue architecture in response to the necrotic tissue, including a fibrous border around the necrotic site, a thickened fibrous capsule (TFC) and a medulla with constricted sinuses (MS) making it difficult to distinguish.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com