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The medium time to early HT was 32 days and was consistent with other studies [6], [23].
Medium time to salvage cystectomy was 19.6 months (range 9.8 82.7months).
Once leukemia relapse occurs, the prognosis is generally poor with the overall 5-year survival of only 5% and medium time to death of 3 4 months.
Time-to-event analyses in phase III trials of regorafenib confirmed clinical experience that, as with sorafenib and sunitinib [ 66], HFSR tends to occur shortly after the start of treatment (median time to first occurrence was 15 days in the phase III study in colorectal cancer [ 67]), and the severity is also likely to peak early (medium time to maximum severity was 22 days in that study [ 67]).
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Among patients in the short or medium time-to-surgery groups, pertrochanteric femoral fracture was the most common type of injury (65.5% and 51.0%) (Table 2).
Start of surgery within 12 hours after the fracture event was considered early surgery (short time-to-surgery), start of surgery from 12 to 36 hours after the fracture event was classified as intermediate (medium time-to-surgery), and surgery that was begun more than 36 hours after the event was considered to be late surgery (longest time-to-surgery).
Under these conditions, the reaction time almost halved and TMS was applied at 50% of subjects' medium reaction time to obtain a timing correspondence with the original experiments.
"Synchronisation binds the medium of time to forms (time binding) and sets out in search of favourable forms.
Fifteen mmol/L 3-amino-1,2,4-triazole (3-AT) was added to the growth medium each time to inhibit low levels of His expression in a leaky manner when a potential candidate was validated.
The medium was changed 3 times during 12 day culture period in 3 days interval, where amount of FBS was reduced by 3% from the differentiation medium each time to reach 1% at the end.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com