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e. Photomicrograph of the surgical specimen (original magnification 100x, H&E stain) illustrates the characteristic histological features of pleomorphic adenoma with medium sized cells with an eosinophilic cytoplasm and myoepithelial cells (small asterisk) partly surrounded by a myxoid matrix (large asterisk).
Positive cells were small to medium sized cells and were diffusely distributed in the latter case.
MPC was first described by Amin et al. in 1994 [ 5] and is characterised by medium sized cells surrounded by an eosinophilic cytoplasm with an irregular distribution of chromatin, frequent mitotic figures and nuclear pleomorphisms [ 5- 8].
FNC of the lymph nodes involved by MF showed a large number of medium sized cells with dense chromatin and irregular shape; the nucleoli were not easily detectable by either Papanicoplaou or Diff Quik stain.
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The latter consisted of quite uniform medium size cells with round nuclei and inconspicuous nucleoli growing in a trabecular or acinar pattern (Fig. 3).
When we injected directly into the brain third ventricle of medium sized fish, cells in the telencephalon, optic tectum, and occasionally in the hypothalamus (not shown) were trans-fected with CMV-GFP (800 ng in 2 μL). Figure 2A shows the general distribution of GFP-expressing cells in a freshly dissected whole brain.
The majority of measured neurons were in the range of small- (diameter < 25 μm) and medium- (25 35 μm) sized cells, with a mean cell diameter between 15 μm and 30 μm.
Ultrastructurally, rMAPC-1 derived progeny presented as clusters of polarized medium sized and large epithelial cells.
Ultrastructurally, hESC-HSF6 derived progeny contained medium sized and large epithelial cells with typical hepatocyte-like phenotype (Figure 3B).
Histological examination showed diffuse wall infiltration by a medium sized, monotonous, atypical lymphoid cell population with scanty basophilic cytoplasm and a characteristic starry-sky pattern.
The neoplastic cells consisted of medium sized atypical lymphocytes with slightly eccentrically located nuclei with coarse chromatin.
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