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IgA appears to be higher in children with the medium exposure level (dynamic cohort 1993 1998) compared to children with lower and higher exposures (convex curve).
One cross-sectional study reported a positive association between PFOS and PFOA and ADHD [ 22], while another study observed an inverse J-shaped association between PFOA and ADHD across quartiles of exposure [ 23], indicating elevated risk of ADHD among those exposed to medium exposure level compared to low exposure level.
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The information level varied and did not always allow distinction between high and medium exposure levels.
Since many of the women did not know if and how often pesticides were used, distinctions between high and medium exposure levels were not always possible and as for cohort 1, these women were categorized as medium exposed.
A zip code was designated as low exposure for noise levels of 50 dB or less (47% of the study population), medium exposure for noise levels greater than 50 dB but 55 dB or less (30%), and high exposure for noise levels greater than 55 dB (23%).
An increased risk of fetal loss in relation to organochlorine exposures has previously been observed in cohorts exposed to relative high or medium level of organochlorines [ 3- 5, 15], whereas other studies including populations at medium or low exposure levels were not able to detect an effect of organochlorines on fetal loss [ 10- 14].
That is, smoking prevalence is often similar at high, medium and low exposure levels.
A summary index of triazine herbicide exposure was developed to classify counties into low, medium, or high exposure levels.
Entomological data led to defining 3 groups of individuals classified by their exposure level (low:1.29±1.11; medium:16.75±3.18; high:31.08±3.47 bites/human/night, mean±SD) as previously described [11].
This was used to allocate each man to a benzene exposure level of "low", "medium", or "high".
We performed two sets of analyses; one which compared the women classified as exposed (exposed from cohort 4 and medium and high exposed from cohort 1, 2, and 3) with the background population, and another which compared two levels of exposure (medium exposure and high exposure) to the background population.
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