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Eleven factors, medium composition and some cultural conditions, were screened.
The medium composition and the reaction conditions were then simultaneously optimized.
Medium composition and culture conditions were optimized using Taguchi orthogonal array (OA) design of experiment (DOE).
Medium composition and culture conditions for α-amylase production were statistically optimized.
Solvent tolerance of the host can be improved by two approaches: modification of medium composition and cell adaptation.
The variation of the medium composition and fermentation conditions also successfully improved the erythromycin productivity [5],[6].
It is widely known that microbial enzyme production is greatly influenced by many factors, especially medium composition and cultivation conditions.
The medium composition and conditions were: Malt extract 20 g/L; Agar 20 g/L; pH 6.5; temperature 25 °C.
Medium composition and fermentation conditions may cause effects on the production of secondary metabolites from the Streptomyces.
By fermentation production of enzymes and growth of microbes, directly related to the medium composition and conditions.
Also, cellular environment, medium composition and dynamic culture system influenced liver-specific functions of hepatocytes beside ECM.
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