Although these hypothesized applications are intriguing, more studies are needed to find empirical support for the possible role of electrophysiological measures in this type of personalized medicine; caution is suggested for any direct clinical application based on these findings and their implications, as more empirical evidence is still needed.
The great teachers in medicine cautioned us against the zeal to heal.
Dr. Eric Topol, a professor of genomics at the Scripps Research Institute in La Jolla, Calif., and author of "The Creative Destruction of Medicine," cautioned that appliances like Knome's would still require personnel steeped in molecular biology and genetics to sift through and evaluate its findings.
However, the history of medicine should caution us to give the most serious consideration to financing basic research, even though it may not be goal oriented.
But an editorial in The New England Journal of Medicine urged caution, pointing out that there were complications with the therapy and that it was too soon to assess its effectiveness.
Given the multiple possible mitigating factors impacting ED mortality and the many potential benefits to patient care associated with the emergence of the specialty of emergency medicine, we caution against using crude ED mortality rates as a measure of the impact and value of EDs in the developing world.
The use of hESCs in regenerative medicine requires caution since aneuploid variants of hESCs spontaneously arise in culture.
Cross-reactivity between non-anaesthetic drugs such as pholcodine or environmental chemicals containing quaternary ammonium groups such as cosmetics and detergents has been proposed as the source of sensitivity to opioids and muscle relaxants: a history of cutaneous sensitivity to cosmetics or rashes from cough medicines should raise caution.
The New England Journal of Medicine last year urged caution because of "unanswered questions, duration of protection, and adverse eff ects that may emerge over time".
But the drug still must be taken in combination with a protease inhibitor or, in patients who have failed protease inhibitors or cannot tolerate the side effects, together with older AIDS medicines, the F.D.A. cautioned.
